| Guest | Team | Date | Position |
|---|---|---|---|
| December 2010 | |||
| John Axford | Brewers | 12/23 | RHP | Derrick Hall | Rockies | 12/9 | President |
| Frank Coonelly | Pirates | 12/2 | President |
| Drew Stubbs | Reds | 12/2 | OF |
| November 2010 | |||
| Troy Tulowitzki | Rockies | 11/30 | SS |
| Neil Walker | Pirates | 11/29 | 2B |
| Clint Hurdle | Pirates | 11/15 | Manager |
| Kevin Towers | D-backs | 11/4 | Executive VP |
| Frank Coonelly | Pirates | 11/3 | President |
| October 2010 | |||
| Derrick Hall | D-backs | 10/7 | President |
| Frank Coonelly | Pirates | 10/6 | President |
| September 2010 | |||
| Reid Nichols | Brewers | 9/17 | Dir. Player Dev. |
| Chuck Greenberg | Rangers | 9/13 | CEO |
| Derrick Hall | D-backs | 9/2 | President |
| Frank Coonelly | Pirates | 9/1 | President |
| August 2010 | |||
| Pedro Alvarez | Pirates | 8/24 | 3B |
| Mike Hazen | Red Sox | 8/18 | Dir. Player Dev. |
| Julio Borbon | Rangers | 8/11 | OF |
| Derrick Hall | D-backs | 8/5 | CEO |
| Frank Coonelly | Pirates | 8/4 | President |
| July 2010 | |||
| Michael Cuddyer | Twins | 7/20 | OF |
| Derrick Hall | D-backs | 7/8 | CEO |
| Frank Coonelly | Pirates | 7/7 | President |
| June 2010 | |||
| Colby Lewis | Rangers | 6/23 | P |
| Armando Galarraga | Tigers | 6/16 | P |
| Damon Oppenheimer | Yankees | 6/15 | VP, Scouting |
| Casey McGehee | Brewers | 6/11 | 3B |
| Neal Huntington | Pirates | 6/11 | GM |
| Jonathan Mayo | MLB | 6/4 | Draft Expert |
| Mark Wilson | Twins | 6/4 | Scout |
| Derrick Hall | D-backs | 6/3 | CEO |
| Frank Coonelly | Pirates | 6/2 | President |
| May 2010 | |||
| Bronson Arroyo | Reds | 5/27 | P |
| Jonathan Mayo | MLB | 5/21 | Draft Expert |
| Justin Smoak | Rangers | 5/20 | 1B |
| Jonathan Mayo | MLB | 5/14 | Draft Expert |
| Denard Span | Twins | 5/11 | OF |
| John Lannan | Nationals | 5/6 | P |
| Frank Coonelly | Pirates | 5/5 | President |
| April 2010 | |||
| Shaun Marcum | Blue Jays | 4/29 | P |
| Nelson Cruz | Rangers | 4/28 | RF |
| Kevin Smith | Twins | 4/27 | Exec. Director |
| Chris Dickerson | Reds | 4/22 | LF |
| Frank Coonelly | Pirates | 4/7 | President |
| Derrick Hall | D-backs | 4/1 | President & CEO |
| March 2010 | |||
| Paul Beeston | Blue Jays | 3/26 | President & CEO |
| Stephen Strasburg | Nationals | 3/17 | RHP |
| Derrick Hall | D-backs | 3/4 | President & CEO |
| Frank Coonelly | Pirates | 3/3 | President |
| February 2010 | |||
| Max Scherzer | Tigers | 2/25 | P |
| Derrick Hall | D-backs | 2/11 | President & CEO |
| Frank Coonelly | Pirates | 2/3 | President |
| January 2010 | |||
| Gregg Zaun, Manny Parra & Carlos Villanueva | Brewers | 1/31 | C, LHP, RHP |
| Brian Anderson | Brewers | 1/29 | Broadcaster |
| Jim Riggleman | Nationals | 1/29 | Manager |
| Mark Lerner | Nationals | 1/27 | Owner |
| A.J. Hinch | D-backs | 1/14 | Manager |
| Frank Coonelly | Pirates | 1/6 | President |
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