| 1. | Albert Pujols | 1B | STL | 1 | 2 | 563 | 103 | 40 | 98 | 11 | .312 | | | | | | |
| The man, the myth, the legend: Albert Pujols has hit 30-plus home runs with 100-plus RBI, and a .310-plus average in all 10 seasons in the Major Leagues. Just 31 years old, Pujols has already compiled 408 hits and 1900 hits. Though his average reached a career-low last season at .312, Pujols remains the creme de la creme, as his greatest obstacle has been pitchers throwing around him. On that note, Pujols will need protection from Matt Holliday and Colby Rasmus to post the numbers expected from him. One of the newer aspects of Pujols' game is his aggressiveness on the basepaths, as the 6'3, 230 lbs. first baseman has swiped 30 bases over the last two seasons. |
| 2. | Adrian Gonzalez | 1B | BOS | 2 | 31 | 582 | 101 | 37 | 90 | 1 | .297 | | | | | | |
| For the first time we will find out just how severe the impact has been for Adrian Gonzalez to play in the extremely pitcher-friendly confines of Petco Park now that he joins the Red Sox sandwiched between well-known sluggers at one of the top hitter ballparks in the Majors. For his career, Gonzalez owns a .442 slugging percentage at Petco Park compared to a .568 SLG on the road. The 28-year old Gonzalez is likely to surpass his previous career-highs of 40 home runs and 119 RBI this season, assuming he can stay healthy. |
| 3. | Miguel Cabrera | 1B | DET | 3 | 3 | 590 | 93 | 38 | 73 | 4 | .306 | | | | | | |
| One of the top three hitters in baseball, Miguel Cabrera is coming off one of his finest seasons with 38 home runs, 126 RBI, and a .328 average. Cabrera is on the fast track to the Hall of Fame, as he enters the season at just 27 years old with 1400 hits, 247 home runs, and a .313 average under his belt. He is equally dangerous against southpaws and right-handers, and very consistent throughout the entire season. He is at his best against Oakland pitching, with nine home runs, 26 RBI, and a .360 average in just 24 games against the A's. |
| 4. | Joey Votto | 1B | CIN | 4 | 4 | 568 | 100 | 33 | 82 | 10 | .298 | | | | | | |
| 5. | Mark Teixeira | 1B | NYY | 6 | 27 | 580 | 98 | 35 | 86 | 1 | .279 | | | | | | |
| 6. | Prince Fielder | 1B | MIL | 13 | 63 | 550 | 88 | 37 | 97 | 2 | .277 | | | | | | |
| 7. | Ryan Howard | 1B | PHI | 19 | 37 | 580 | 88 | 38 | 70 | 3 | .260 | | | | | | |
| 8. | Kevin Youkilis | 1B | BOS | 26 | 73 | 514 | 80 | 27 | 72 | 5 | .286 | | | | | | |
| 9. | Adam Dunn | 1B | CWS | 30 | 45 | 554 | 81 | 42 | 104 | 1 | .256 | | | | | | |
| 10. | Justin Morneau | 1B | MIN | 33 | 98 | 526 | 78 | 25 | 71 | 1 | .289 | | | | | | |
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