ARLINGTON -- Jordan Lyles left Tuesday night's game with a one-run lead after seven innings, set to earn his first career Major League win. One batter into the eighth inning, his magical night disappeared.
Josh Hamilton tied the game with a home run off Sergio Escalona, and the Rangers walked off in the 11th inning on a solo shot from Mitch Moreland against Enerio Del Rosario, as the Astros' bullpen blew its Major League-leading 15th save in a 5-4 loss.
"You can't let up any time with any lineup, but this one will make you pay for it," Lyles said.
Escalona pitched only to Hamilton and was one of four relievers used in the eighth inning. After Fernando Rodriguez allowed two men to reach while retiring a batter, Fernando Abad entered and recorded an out. Then Del Rosario (0-2) finished the frame and threw 2 1/3 scoreless innings before allowing the walk-off shot to Moreland.
"We battled tonight, put ourselves in the situation to do this, so I was happy to be the one who came through," Moreland said.
Lyles was up, 4-2, as he entered his final inning before allowing an RBI triple to Endy Chavez with two outs and a walk to Ian Kinsler. With runners on the corners, Lyles struck out Elvis Andrus to preserve the lead.
Lyles recorded his third quality start of his brief Major League career, earning a no-decision.
"I did a pretty good job of limiting my hits in the different innings," he said. "I probably gave up multiples one inning or two innings, but for the most part a single shot here, a single shot there, gave our team a chance to win."
The Astros stretched their homerless streak to eight games, while the Rangers had no trouble reaching the seats.
Four of Texas' five runs on Tuesday came courtesy of solo blasts, including their first two runs on Lyles. The first home run came off the bat of Michael Young in the second inning.
"If I'm going to give them up, glad no one is on base," Lyles said. "That was the positive side. The one to Michael I just left over the plate."
Houston's 20-year-old starter fanned six Rangers and allowed three runs on seven hits, outlasting C.J. Wilson, who allowed four runs in 6 2/3 innings.
The Astros were no strangers to facing southpaws. Tuesday night marked the 23rd time they battled a left-handed starter this season. Jeff Keppinger leads the club with a .458 batting average against southpaws this season, and Jason Bourgeois leads the team with a .463 on-base percentage against lefties.
Both players backed up their stats, as Keppinger went 3-for-5 with two RBIs and Bourgeois went 3-for-5 with a run.
Michael Bourn didn't have any issues off a fellow lefty either, going 3-for-5 with two runs and two RBIs. Bourn doubled and scored in the first inning on an RBI single by Keppinger.
It's the first time each of the top three hitters in Houston's lineup have had three hits apiece since Sept. 5, 2000.
"I was able to get some hits tonight, but Kepp was able to drive in some runs, too, and Jason was able to get it started," Bourn said. "It wasn't just me, but I had some things to do with it."
Bourn put the Astros back on top, 2-1, in the third inning on his second double, scoring Bourgeois, who had doubled off the left field wall. Bourn scored on Keppinger's second RBI single in the first three innings.
Bourn also added the Astros' fourth run of the game in the seventh inning with an RBI single on a chopper past Moreland at first, but it wasn't enough insurance for the Astros' bullpen.
"It's frustrating, but when you play a team like this, you've got to try to continue to pour it on," Bourn said. "We couldn't continue to pour it on. They've got some people over there that can swing."
The Rangers have now won four games in a row against the Astros and seven of their past eight since the start of 2010.
Rowan Kavner is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.