PHOENIX -- It is hard to imagine a more painful loss -- both on and off the field -- than the one the D-backs endured Wednesday night.
Arizona lost starting shortstop Stephen Drew to a season-ending injury and then was unable to capitalize on a golden scoring opportunity in the ninth before falling, 5-2, to the Brewers in 10 innings at Chase Field.
"It was a tough night overall," starter Joe Saunders said. "We lost the game and we lost our starting shortstop. We're going to have to regroup, bounce back and put it behind us as best we can. We shouldn't have lost that game. These games are tough. You look back on these games you should have won in late September, and we should have won that game."
For the second night in a row, the D-backs came out of the gate sluggish, but Saunders did his part to keep his teammates in the game.
The left-hander was outstanding in allowing just two runs and scattering five hits over seven innings.
The Brewers did grab the early 1-0 lead when Ryan Braun homered to left-center with two outs in the first inning.
"One bad pitch to Braun, just a bad located fastball there, and a good hitter is usually going to do that to you," Saunders said. "So, minimize the damage -- one run -- then try to put up as many zeroes as I can and keep us in the game."
That's exactly what Saunders did as he continued to put up zeroes until the seventh, when he allowed a two-out RBI single to Jonathan Lucroy to put the Brewers ahead, 2-0.
By that point the game itself seemed irrelevant given the serious nature of Drew's injury.
While attempting to score from second on Chris Young's double to left in the fourth inning, Drew, who ran through a stop sign from third-base coach Matt Williams, slid into home plate and was tagged out by Lucroy. During his slide, Drew seemed to catch the tip of his right foot and his ankle rolled underneath him, fracturing the joint.
More tests will be performed Thursday, but Drew will miss the rest of the 2011 season and will need surgery.
On the very next play, Milwaukee center fielder Carlos Gomez fractured his left clavicle when he made a diving catch on Ryan Roberts' fly ball.
Brewers starter Chris Narveson kept the D-backs off balance while cruising through seven innings. The lefty allowed just four hits and retired the final 10 hitters he faced before Milwaukee manager Ron Roenicke lifted him in favor of Francisco Rodriguez to start the eighth.
The pitching change proved to be what the D-backs needed to get their bats going, as they rallied for a pair of runs to tie the game.
The big blow of the inning was a two-run double by Willie Bloomquist -- who figures to get the bulk of the playing time at short in Drew's absence -- which came on the heels of pinch-hitter Geoff Blum drawing a key walk.
"He fell behind 3-0 and I was taking 3-0, and I got to 3-1 and I was just looking for one pitch in one spot, so I was able to put a good swing on it and I hit a ball in the gap," Bloomquist said.
It looked like the D-backs might ride that momentum to a win when Justin Upton led off the bottom of the ninth with a double and advanced to third on a wild pitch with no outs.
The Brewers brought in Braun from left field and stationed him up the middle, giving them five infielders.
Takashi Saito, though, was able to somehow wiggle out of the jam, as he got Young and Roberts to ground to third, and, after an intentional walk, pinch-hitter Sean Burroughs flew out to end the inning with Upton still at third.
"We let that game [get] away," Gibson said. "We had a golden opportunity, had a guy on third, nobody out, they had five infielders and you know they're looking for a ground ball. You have to elevate the ball. We didn't execute that part of it. If we want to get to the playoffs and have an opportunity to get to the World Series, we have to get better at this stuff."
The Brewers broke through in the 10th, scoring three runs off Ryan Cook, who was making his Major League debut after being called up from Double-A Mobile earlier in the day.
"It was kind of an emotional roller coaster," Braun said. "You don't really see that too much in the course of one game. Obviously, big injuries on both sides of the ball. Comebacks by both teams. It was a really big win for us."
And a pair of really painful losses for the D-backs.
Steve Gilbert is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.