Milwaukee is currently one game ahead of the D-backs, who clinched the National League West on Friday, in the standings.
"We're still playing for something, so we need to play some good ball to try to win as many games as we can to make sure we have that home-field advantage, and also to carry this on into the playoffs," Brewers manager Ron Roenicke said.
The Brewers can take a step toward that goal with Greinke on the hill. In his last start against the Reds, Greinke allowed one run on two hits in seven innings with 10 strikeouts for the win. The former Cy Young winner has a 1.93 ERA over his last five starts and has been excellent at Miller Park, where he is 10-0 with a 2.89 ERA. The Brewers have won all 13 of his Miller Park starts. Overall, he has a 3.75 ERA.
Greinke celebrated his first clinch experience in his eight-year career Friday. He was looking for more.
"We're looking to play in the playoffs, not just get there," he said. "But it is fun.
"Hopefully, our intensity is as high as ever [over the remaining regular-season games]. We should be good. I wouldn't expect anything less."
Before Friday's game, Marlins manager Jack McKeon had a conversation with Roenicke.
"I just told Roenicke, I know the Phillies are good, but I made the remark that, in my book, these guys are the sleepers," McKeon said. "I like their hitting. The Phillies aren't hitting, and [Milwaukee's] pitching isn't too far behind the Phillies. They've got a pretty good staff, and they've got a pretty good bullpen."
Florida right-hander Alex Sanabia (0-0) will make his second start of the season.
The 23-year-old received a no-decision after allowing one run on six hits in six innings against the Phillies in Game 2 of a doubleheader on Sept. 15. Sanabia has taken over for Brad Hand in the rotation.
Sanabia has never faced Milwaukee, but McKeon hopes he handles it in the same manner he did against Philadelphia.
"He showed us that he had a lot of poise, and he had good command," McKeon said. "That's what I liked about him. He challenged the hitters. That's what I liked about him. Now, whether he can do it again, we'll find out."
Marlins: Win shy of road record
With one more win in its final two road games, Florida will match the second-most road victories in club history (41 in 2004). The franchise record is 44, in 2009.
At 40-39, the Marlins are one of just seven teams in the NL to have a record over .500 on the road.
However, in home games during the final year at Sun Life Stadium, Florida is 31-47.
Left-handed hitters are 7-for-23 (.304) against lefty reliever Mike Dunn in his last 17 games.
Since the All-Star break, Omar Infante is 66-for-210 (.314) with 20 multi-hit games.
Brewers: Closing in on franchise record
Milwaukee is just one win shy of tying the franchise record for home wins in a season with five games remaining.
At 53-23 (.697), the Brewers lead the Majors in home winning percentage. In 1978, the Brewers went 54-27. They did not lose consecutive home games until their 42nd game, the longest streak to begin a season since the 1996 Yankees.
Last season, Milwaukee went 40-41 at Miller Park, including 13-13-0 in series play.
John Axford is one save shy of setting the single-season franchise record. He is tied with Francisco Cordero (44 in 2007) after nailing down the save in Friday's victory.
Rickie Weeks is 5-for-24 (.208) since coming off the disabled list and appearing in 10 games.
Florida is 1-7 over its last eight games against Milwaukee at Miller Park.
Prince Fielder is 5-for-17 (.294) with four homers and eight RBIs this season against the Marlins.