Hudson reached the milestone on Friday against the Astros, tossing 7 1/3 innings and surrendering just one run on four hits while throwing a season-high 116 pitches.
On a roll his last four starts, Hudson has won all four games, combining to allow just eight runs in 27 1/3 innings.
"If I don't get into at least the seventh inning, I don't think I've done my job," said Hudson, whose career record is 192-101.
After the Phillies' 3-0 win over the Braves on Tuesday -- their first victory in the last eight meetings with Atlanta -- Philadelphia will send Kyle Kendrick to the hill hoping he can deliver a series win.
In and out of Philadelphia's rotation this season, Kendrick is back in a starting role after Joe Blanton was traded to the Dodgers last week.
The Phillies eased Kendrick back into the rotation during his last start against the D-backs, in which he tossed 63 pitches in four innings of work. In his first start since July 6, the right-hander allowed three runs on five hits for the loss.
While Kendrick's pitch count will increase on Wednesday, the team is still unsure what his role will be the rest of the season.
"I definitely was throwing good out of the bullpen. But I'm happy to be starting again, that's for sure," Kendrick said. "I think they already know a lot about me. I just have to go out there and pitch good."
Braves: Uggla gets day off
Even with a two-hit game on Monday, Dan Uggla was out of Tuesday's starting lineup against Phillies left-hander Cole Hamels.
With Uggla batting just .145 (8-for-55) in his career against Hamels, manager Fredi Gonzalez felt it was the right time to give Uggla a night off. Encouraged by Uggla's progress at the plate the last few weeks, even though the second baseman is hitting just .139 with two home runs since June 5, Gonzalez didn't want to chance it.
"I told him I think he's had some great at-bats, but I didn't want Hamels [messing] him up," Gonzalez said. "It's like having good at-bats, and then you face a knuckleballer and they screw you up for a while."
Phillies: Polanco not ready to return
Although his back is feeling better, Phillies third baseman Placido Polanco said on Tuesday that he is still unsure of when he will return to the field.
Polanco has been on the 15-day disabled list with lower back inflammation since July 23 and was eligible to be activated on Tuesday. However, he still hasn't been cleared to field ground balls and will need more time than 15 days.
"I think that once he starts taking ground balls, that will be an indication that he's moving along," manager Charlie Manuel said before Tuesday's game against the Braves.
The Braves have the second-best winning percentage in the Majors since the All-Star break with a record of 17-8.
Braves first baseman Freddie Freeman has 33 two-out RBIs this season, which ranks third in the Majors.
In 14 starts this season, Kendrick has a 4.54 ERA and a .285 opponents' batting average.