The White Sox lead the Tigers by two games in the American League Central.
Both teams will fly in for a 1:10 p.m. CT start at U.S. Cellular Field. The Sox will be coming back from Minnesota, while the Tigers will take the short flight from Cleveland.
For the Tigers, it will be Doug Fister (9-8, 3.49 ERA) getting the call. Two of Fister's last three starts have come against Chicago. He threw five innings and allowed three runs -- two earned -- on four hits in a no-decision on Aug. 31. He gave up two hits -- both solo home runs -- in seven innings to earn the win on Tuesday against Chicago.
"It's definitely a step in the right direction," said Fister, who has been battling injuries for most of the season, including a recent groin strain. "I don't want to say I'm in midseason form, but I'm still trying to make as many adjustments as possible."
The Sox will go with 23-year-old rookie Jose Quintana (6-4, 3.52 ERA), who was pushed back from Saturday's scheduled start and will be going on six days' rest.
Quintana's first year in the big leagues has unquestionably been impressive, but his mettle will be tested as he pitches in one of the biggest games of the season. If his last outing is any indication -- he fired 7 2/3 innings of one-run ball vs. Detroit last Monday -- he should be just fine.
"I don't see it as putting pressure on myself," Quintana said through an interpreter Sunday. "I see it as another game, that's kind of how I go about each outing. But I know it's an important game for us, and so I'm going to go out there and do the best I can and try to help this team get a win."
Tigers: Fister has been successful at U.S. Cellular Field
Fister is 1-2 with a 3.35 ERA in six career starts against the White Sox. He is 1-0 with a 2.40 ERA in two starts at U.S. Cellular Field.
Austin Jackson was a late scratch from Sunday's lineup with a sore left ankle. Jackson was injured jumping into the center-field wall attempting to save Anibal Sanchez's no-hit bid in the seventh inning on Saturday. It's possible he could miss Monday's game.
"I guess just the impact of it was what I was feeling afterwards," Jackson said.
Outfielder Quintin Berry, who was already in the lineup but moved over to center field, started his second game in a row for the Tigers on Sunday after not starting two consecutive games since Aug. 3-4 -- also against Cleveland.
White Sox: Pierzynski gets day off as prep for Detroit
Catcher A.J. Pierzynski was given the day off Sunday to ensure he would be fresh for Monday's game. Pierzynski has started 121 of Chicago's 145 games this season, and has 108 starts at catcher. Tyler Flowers served as his replacement.
"Guys are tired, so you're just trying to make sure you're still strong," manager Robin Ventura said.
Pierzynski is 1-for-17 in his career against Fister, but Ventura had no hesitations about Pierzynski playing.
"A.J. will be playing tomorrow," Ventura said.
Adam Dunn missed Chicago's past five games against the Tigers with an oblique strain, but after returning Saturday, he should be set for Monday's game. He is 10-for-46 (.217) against Detroit this year, with three doubles, three home runs and seven RBIs.
Tigers catcher Alex Avila was removed from Sunday's game after taking an elbow to the jaw from Prince Fielder. He is listed as day to day, although the club announced he experienced no concussion symptoms.