After navigating a 10-game losing streak earlier this month and starting their recent nine-game road trip 1-6, the Twins have regrouped at the expense of the Brewers.
The Twins won two games in Milwaukee before taking the first of two in Minnesota on Wednesday. They look to win all four games of the home-and-home Interleague set Thursday at Target Field.
Kyle Lohse, who returns to the Brewers' rotation Thursday after missing a start with right elbow irritation, will square off against his former team. Should he beat the Twins, Lohse would join only 12 other pitchers in baseball history who have defeated all 30 Major League teams -- Al Leiter, Kevin Brown, Terry Mulholland, Curt Schilling, Woody Williams, Jamie Moyer, Randy Johnson, Barry Zito, Javier Vazquez, Vicente Padilla, Derek Lowe and A.J. Burnett.
Lohse is 1-5 this season despite a respectable 3.76 ERA. The Twins are the only team the right-hander has never faced.
He'll encounter what should be a more rested Minnesota lineup.
Tuesday's game at Miller Park was a tough get for Minnesota, lasting 14 innings and nearly five hours before the Twins outlasted the Brewers, 6-5. The Twins did not get back into Minnesota until after 2 a.m. CT on Wednesday.
"We got in pretty late last night, but it's always good to be home and at our ballpark," Twins manager Ron Gardenhire said before Wednesday's game.
Gardenhire sat Justin Morneau and had Joe Mauer in the lineup at designated hitter Wednesday after each played all 14 innings Tuesday, with Mauer catching the entire game.
"We're a little beat up, but we have to find a way," Gardenhire said. "We've got some guys who need a break. We've played 26 out of the past 27 days with road trips and the whole package."
Twins: Walters looks for repeat of season debut
P.J. Walters impressed in his season debut against the Tigers on Saturday, allowing eight hits and two earned runs in six innings.
The right-hander will try to match the effort in his first career start against the Brewers.
Brewers: Segura cools down after big day
Jean Segura tied a franchise record with six singles Tuesday but went 0-for-3 in his curtain call Wednesday.
Gardenhire had high praise for Segura before Wednesday's game.
"Oh my, he hits everything you throw up there," Gardenhire said. "He's got one of the shortest, most compact swings you'll ever see. He seems to be on everything.''
• Twins third baseman Trevor Plouffe was activated from the seven-day concussion list Wednesday but scratched from the game because of a left calf tightness and is day to day.
• Brewers relievers have a 2.01 ERA in the last 21 games, a span covering 85 innings pitched. The bullpen has allowed 19 earned runs in the streak, lowering its ERA from 4.16 to 3.11.
• The Brewers are 5-21 in May, their worst record in any month since they went 6-21 in August 2004. Milwaukee needs to win its final two games of the month, against the Twins on Thursday and Phillies on Friday, to avoid matching the lowest winning percentage of any month in franchise history, dating back to 1969.
Kevin Massoth is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.