The Padres lost their second pitcher in a week to the disabled list thanks to a sore elbow as Friday's scheduled starter, Robbie Erlin, was placed on the 15-day disabled list on Thursday.
Last Friday, starter Andrew Cashner also landed on the DL with a sore elbow. Donn Roach got the start in his place.
When the Padres play the Cubs in the second game of their four-game series at Petco Park, long reliever Tim Stauffer, making his first start of the season, will take Erlin's spot on the mound .
Stauffer hasn't started a Major League game since May 14, 2012. He landed on the DL four days after that start with an elbow injury of his own, which eventually needed surgery.
Manager Bud Black, for one, likes what Stauffer has done for the Padres in long relief. There's a comfort level there, he said.
"Stauffer has shown his ability to pitch out the 'pen and appear in multiple occasions in a given week," Black said.
Stauffer -- the longest tenured Padre -- has made 70 starts in his career, including 31 in 2011. He went 9-12 with a 3.73 ERA.
Stauffer will be on a pitch count on Friday and will likely throw around 60 pitches.
Padres: Smith staying hot in May
Outfielder Seth Smith has continued his torrid pace in the month of May. Going into Thursday's game, Smith had a .376/.471/.634 line with 11 doubles, three triples, three home runs 14 RBIs and 19 walks in is last 31 games.
In that span, his batting average leads the Majors, his on-base percentage ranks second and his slugging percentage is fifth.
In May alone, he has a .439/.529/.842 line, the highest batting average, OBP and slugging percentage in the Majors. Smith's .439 average this month is second in team history behind only Tony Gynn's .449 average in May 1997.
"He's on a roll right now, especially over the last couple of weeks," Black said. "Seth has the ability to hit fastballs. He's laying off breaking balls, and he has a patient approach to start with. He's not afraid to hit with two strikes."
Cubs: Jackson riding quality streak
Friday's starter Edwin Jackson is aiming to keep his run of quality starts going when he takes the hill against the Padres.
Jackson (3-3) has notched quality starts in each of his last three outings dating back to a no-decision against the White Sox on May 6.
His last outing was arguably his best of the season.
Against the Brewers at Miller Park, Jackson gave up only four hits and walked one while striking out 11 batters -- a season-high for the 30-year-old right-hander.
"I just got in a groove, [catcher Welington Castillo] and myself early in the game," Jackson said after the May 17 win. "We were able to come out and make pitches and let the defense play behind us."
Through nine starts in his second year with the Cubs, Jackson has improved mightily. A year after leading the National League with 18 losses, his ERA is down from 4.98 in 2013 to 3.98 this season.
• Padres second baseman Jedd Gyorko is continuing to slump this season. In his last 10 games, he has hit .111 (4-for-36). However, he is 4-for-6 lifetime against Jackson with a double, a home run and five RBIs.
• Cubs reliever Carlos Villanueva notched a three-inning save against the Padres on Thursday. It was his first save since he picked up a save for the Brewers against the Pirates on May 20, 2010.
Adam Lichtenstein is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.