Transactions| Date | Transaction | |||
| 4/30/01 | Ken Griffey Jr.: Placed CF Ken Griffey Jr. on the 15-day disabled list with a partial tear in his left hamstring. | |||
| 4/29/01 | Optioned RHP Matt Skrmetta back to Louisville (Class AAA). | |||
| 4/26/01 | D.T. Cromer: Optioned INF D.T. Cromer back to Louisville (Class AAA) | |||
| Purchased the contract of RHP Matt Skrmetta from Louisville (Class AAA) | ||||
| 4/15/01 | Scott Winchester: Placed RHP Scott Winchester on the 15-day disabled list with a strained oblique muscle on his left side. | |||
| Jim Brower: Recalled RHP Jim Brower from Louisville (Class AAA). | ||||
| 4/10/01 | D.T. Cromer: Purchased the contract of IF D.T. Cromer from Louisville (Class AAA). | |||
| Hector Mercado: Recalled P Hector Mercado from Louisville (Class AAA). | ||||
| 4/9/01 | Major League Baseball voids P Justin Atchley's Major League contract due to rule violation; Atchley is outrighted to Louisville (AAA) | |||
| Wilton Guerrero: IF/OF Wilton Guererro outrighted to Louisville (AAA). | ||||
| 4/6/01 | LHP Justin Atchley recalled from Louisville (AAA) | |||
| Rob Bell: RHP Rob Bell reassigned to Louisville (AAA) | ||||
| 4/4/01 | Scott Winchester: Purchased the contract of RHP Scott Winchester from Louisville (AAA) | |||
| Scott Williamson: Placed RHP Scott Williamson on the 60-day disabled list | ||||
| 4/2/01 | Ed Yarnall: Sold LHP Ed Yarnall to the Orix Blue Wave for $300K | |||