|5/31/08||Activated RHP Clay Buchholz from the 15-day disabled list and optioned him to Triple-A Pawtucket.|
|5/30/08||Placed RHP Daisuke Matsuzaka on 15-day disabled list, retroactive to May 28, with mild right rotator cuff strain and purchased the contract of INF/OF Jeff Bailey from Triple-A Pawtucket.|
|5/25/08||Sent RHP Clay Buchholz to Triple-A Pawtucket on rehab assignment.|
|5/23/08||Activated OF Brandon Moss from the 15-day disabled list and optioned him to Triple-A Pawtucket.|
|5/21/08||Purchased the contract of RHP Bartolo Colon from Triple-A Pawtucket; Optioned RHP Justin Masterson to Triple-A Pawtucket.|
|5/20/08||Sent RHP Julian Tavarez outright to Triple-A Pawtucket, he had been designated for assignment on May 12, he refused the assignment and is a free agent; Optioned RHP Chris Smith to Triple-A Pawtucket; Recalled RHP Justin Masterson from Double-A Portland; Optioned RHP Justin Masterson to Triple-A Pawtucket.|
|5/19/08||Optioned RHP Chris Smith to Triple-A Pawtucket.|
|5/18/08||Recalled RHP Chris Smith from Triple-A Pawtucket; optioned OF Jonathan Van Every to Pawtucket.|
|5/14/08||Placed RHP Clay Buchholz on the 15-day disabled list with a broken nail on his right middle finger; Recalled OF Jonathan Van Every from Triple-A Pawtucket.|
|5/12/08||Activated 1B Sean Casey off the 15-day disabled list and designated RHP Julian Tavarez for assignment.|
|5/11/08||Activated INF Alex Cora from 15-day disabled list and optioned INF Jed Lowrie to Triple-A Pawtucket; Traded RHP Bryan Corey to the San Diego Padres in exchange for a player to be named later or cash considerations.|
|5/5/08||Placed OF Brandon Moss on the 15-day disabled list, retroactive to May 3, after undergoing an appendectomy; Recalled RHP Craig Hansen from Triple-A Pawtucket.|
|5/1/08||Sent RHP Bryan Corey outright to Triple-A Pawtucket, he had been designated for assignment on April 29.|
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