| Date | Transaction | |||
| 12/26/07 | Signed RHP Mark Prior to a one-year contract. | |||
| 12/20/07 | Signed C Michael Barrett to a one-year contract. | |||
| 12/19/07 | Signed free agent 1B Robert Fick and free agent OF Jeff DaVanon to Minor League contracts with invitations to Spring Training. | |||
| 12/18/07 | Signed INF Tadahito Iguchi to a one-year contract. | |||
| 12/15/07 | Acquired OF Jim Edmonds and cash from the Cardinals in exchange for Minor League 3B David Freese. | |||
| 12/14/07 | Signed LHP Shawn Estes and LHP Glendon Rusch to Minor League contracts with invitations to Spring Training. | |||
| 12/12/07 | Signed RHP Jake Peavy to a five-year contract with a club option for 2013; Did not offer 2008 contracts to RHP Jack Cassel, LHP Ryan Ketchner, 3B Morgan Ensberg and OF Jason Lane, making them free agents. | |||
| 12/10/07 | Signed free agent LHP Randy Wolf to a one-year contract. | |||
| 12/7/07 | Free agent C Michael Barrett accepted arbitration and returned to the Padres. | |||
| 12/6/07 | Selected RHP Michael Gardner from the Yankees and 2B Callix Crabbe from the Brewers in the Rule 5 Draft; Acquired RHP Carlos Guevara from the Marlins for cash. | |||
| 12/5/07 | Sold the rights to OF Terrmel Sledge to the Hokkaido Nippon Ham Fighters of Japan's Pacific League in exchange for cash considerations. | |||
| 12/1/07 | Offered arbitration to OF Mike Cameron and C Michael Barrett and declined to offer arbitration to OF Milton Bradley. | |||
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