CHICAGO -- The adjustment to any sort of prolonged inactivity will be tough enough for Paul Konerko over the next few weeks, as he makes his first career trip to the 15-day disabled list.

Having that trip cost him the opportunity to play in both upcoming weekend series against the Cubs makes the extended absence that much more difficult.

"Yeah, that's a big one. It kind of couldn't be worse. Those are the most fun games we have all year," said Konerko, who was placed on the disabled list Tuesday, retroactive to June 15, with a Grade 1 strain of his left oblique muscle. "And I've always played well in those games. I've always had good moments. It's definitely going to be odd watching.

"Thanks for bringing that up," added Konerko to the group of reporters assembled around his locker prior to Tuesday's series opener with the Pirates.

Konerko has done extremely well in Interleague Play, leading the franchise in career batting average, home runs and RBIs. He is hitting .303 with 14 home runs ad 37 RBIs against the Cubs, but when the Cubs and White Sox look to break their 30-30 all-time tie Friday afternoon at Wrigley Field, Konerko will join Cubs left fielder Alfonso Soriano as an injured spectator.

With southpaw Ted Lilly on the mound for the Cubs, Brian Anderson has a shot to get the starting nod in center field. Anderson missed last year's contests while playing for Triple-A Charlotte, and he had an early exit from a game between the two on May 20, 2006, when Anderson was ejected for fighting with John Mabry. The fight started when Michael Barrett threw a sucker punch at A.J. Pierzynski, after Pierzynski plowed him over at the plate.

"When I'm not getting thrown out of a game, it's actually pretty exciting," said Anderson with a laugh. "I'm going to try to do my best this year to keep my composure and not get caught up in the moment like I did a couple of years ago. It seems like a fun series, so I'm going to try not to miss it."