TUCSON -- Jayson Nix's sizzling spring has been put on hold and might be over altogether.

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The White Sox infielder, battling for the second-base job, re-injured the strained right quadriceps that he suffered during Chicago's March 4 game against the Cubs in Las Vegas and could be out until after the regular season starts.

Nix, 26, aggravated the quad while legging out a double in Tuesday's 7-6 loss to the D-backs at Tucson Electric Park, and manager Ozzie Guillen said the team will now give Nix all the time he needs to get healthy again.

"I'm kind of worried about him," Guillen said. "With that type of injury, it's hard to recover quick. Right now, we should give him enough time, no matter what stage of Spring Training, to get him healthy."

With a hands-off approach to this sensitive, unpredictable type of injury, it appears time is running out to get ready for Opening Day for Nix, who was signed by the Sox as a free agent last October after playing in 22 games for the Rockies in 2008.

Nix has been competing for the second-base job with Gordon Beckham, Chris Getz and Brent Lillibridge and responding to the challenge. After Tuesday, Nix had a .462 spring batting average in the seven games he'd been healthy enough to play in.

"He was playing good, making all the plays," Guillen said.

"Now it's best for the team and him to make sure he heals completely."