Melky Cabrera hit his third homer of the spring and added a single among three at-bats. (Marcio Jose Sanchez/AP)

SCOTTSDALE, Ariz. -- In a game that saw Giants stars Buster Posey and Freddy Sanchez return to action after injury-marred 2011 seasons, the Giants claimed a 6-3 victory over the Reds at Scottsdale Stadium on Friday afternoon.

Outfielder Melky Cabrera continued his torrid spring with a 2-for-3 day at the plate, including his third homer in Cactus League play, to lead the Giants offensively.

Giants right-hander Matt Cain earned the victory with three sharp innings, his longest outing of the spring. After lefty Aroldis Chapman held the Giants hitless through two innings, striking out two, the loss went to Reds right-hander Sam LeCure, who allowed four earned runs on five hits in two innings of work.

Posey, out since last May 25 with a leg injury, caught two of Cain's three innings and flied out to right in his only at-bat.

"I was just anxious to play," Posey said. "I've been looking forward to playing for some time now, so I was just happy to be out there."

Sanchez, recovering from a shoulder injury, made his first appearance as a DH, going 1-for-4 with a single.

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In the third, Cabrera hit a two-run homer off LeCure, depositing the ball deep over the right-field fence with the switch-hitter batting from the left side. That drove home Brandon Crawford, who had drawn a two-out walk. Cabrera is now batting .588 (10-for-17) in his first spring with the Giants.

Brett Pill's double and Nate Schierholtz's single gave the Giants a 4-0 lead before the Reds scored their first run in the fifth on a Juan Francisco single. Todd Frazier added a solo homer in the sixth, his first of the spring. Brandon Belt slugged his second homer of the spring in the eighth.

Reds up next: The Reds will travel to Phoenix to meet the A's on Saturday, and it could be the much-anticipated debut of Cuban outfielder Yoenis Cespedes for Oakland. Cespedes isn't being welcomed to the Majors easily since Cincinnati is scheduled to start hard-throwing ace Johnny Cueto. In his first outing vs. the Indians, Cueto gave up one run and two hits over two innings but looked good. The Reds are also sending Brandon Phillips, Ryan Ludwick and Chris Heisey on the trip.

Giants up next: The Giants will play their second split-squad set of games Saturday, hosting the Brewers and traveling to play the Angels. In Scottsdale, Barry Zito will make his second Cactus League start, following up on a two-inning start that included 28 strikes among his 35 pitches. In Tempe, right-hander Shane Loux will get the start for the Giants, who will face C.J. Wilson in his second start with the Angels after signing as a free agent from the Rangers. Freddy Sanchez will serve as the Giants' designated hitter for the second straight game.