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04/08/12 8:46 AM ET

Third-base prospect Rendon suffers ankle injury

CHICAGO -- Class A Potomac third baseman Anthony Rendon suffered a badly sprained left ankle while running the bases in a 7-2 loss to Lynchburg on Saturday. It's not known how many games he will miss.

Rendon hurt the ankle in the fourth inning after a hitting a double and trying to score on a bloop single to center by Justin Bloxom. The Nationals' No. 2 prospect went down with the ankle injury after rounding third base.

Rendon has had a history of injuries, including shoulder and ankle problems. However, that didn't stop the Nationals from making him their top pick in the 2011 First-Year Player Draft.

In 63 games with Rice University last year, Rendon hit .327 with six home runs, 27 RBIs and an on-base percentage of .520.

Thus far, Rendon has played in two games for Potomac and is 2-for-4 with a run scored.

Bill Ladson is a reporter for MLB.com and writes an MLBlog, All Nats All the time. He also could be found on Twitter @WashingNats. This story was not subject to the approval of Major League Baseball or its clubs.