| Date | Opponent | Time | TV | Radio |
|---|---|---|---|---|
| Monday, May 20 | @San Diego | 9:10 PM | FS-M | KMOX 1120 |
| Tuesday, May 21 | @San Diego | 9:10 PM | FS-M | KMOX 1120 |
| Wednesday, May 22 | @San Diego | 9:10 PM | FS-M | KMOX 1120 |
| Friday, May 24 | @LA Dodgers | 9:10 PM | FS-M | KMOX 1120 |
| Saturday, May 25 | @LA Dodgers | 6:15 PM | FOX | KMOX 1120 |
| Sunday, May 26 | @LA Dodgers | 3:10 PM | FS-M | KMOX 1120 |
| Monday, May 27 | @Kansas City | 1:10 PM | FS-M | KMOX 1120 |
| Tuesday, May 28 | @Kansas City | 7:10 PM | FS-M | KMOX 1120 |
| Wednesday, May 29 | vs. Kansas City | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, May 30 | vs. Kansas City | 7:15 PM | FS-M | KMOX 1120 |
| Friday, May 31 | vs. San Francisco | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, June 1 | vs. San Francisco | 6:15 PM | FOX | KMOX 1120 |
| Sunday, June 2 | vs. San Francisco | 1:15 PM | FS-M, TBS | KMOX 1120 |
| Monday, June 3 | vs. Arizona | 7:15 PM | FS-M | KMOX 1120 |
| Tuesday, June 4 | vs. Arizona | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, June 5 | vs. Arizona | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, June 6 | vs. Arizona | 6:15 PM | FS-M | KMOX 1120 |
| Friday, June 7 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Saturday, June 8 | @Cincinnati | 6:15 PM | FOX | KMOX 1120 |
| Sunday, June 9 | @Cincinnati | 7:05 PM | ESPN | KMOX 1120 |
| Tuesday, June 11 | @NY Mets | 6:10 PM | FS-M | KMOX 1120 |
| Wednesday, June 12 | @NY Mets | 6:10 PM | FS-M | KMOX 1120 |
| Thursday, June 13 | @NY Mets | 12:10 PM | FS-M | KMOX 1120 |
| Friday, June 14 | @Miami | 6:10 PM | FS-M | KMOX 1120 |
| Saturday, June 15 | @Miami | 3:10 PM | FS-M | KMOX 1120 |
| Sunday, June 16 | @Miami | 12:10 PM | FS-M | KMOX 1120 |
| Monday, June 17 | vs. Chi Cubs | 6:05 PM | FS-M | KMOX 1120 |
| Tuesday, June 18 | vs. Chi Cubs | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, June 19 | vs. Chi Cubs | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, June 20 | vs. Chi Cubs | 7:15 PM | FS-M | KMOX 1120 |
| Friday, June 21 | vs. Texas | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, June 22 | vs. Texas | 6:15 PM | FOX | KMOX 1120 |
| Sunday, June 23 | vs. Texas | 1:15 PM | FS-M | KMOX 1120 |
| Tuesday, June 25 | @Houston | 7:10 PM | FS-M | KMOX 1120 |
| Wednesday, June 26 | @Houston | 7:10 PM | FS-M | KMOX 1120 |
| Friday, June 28 | @Oakland | 9:05 PM | FS-M | KMOX 1120 |
| Saturday, June 29 | @Oakland | 3:05 PM | FS-M | KMOX 1120 |
| Sunday, June 30 | @Oakland | 3:05 PM | FS-M | KMOX 1120 |
| Tuesday, July 2 | @LA Angels | 9:05 PM | FS-M | KMOX 1120 |
| Wednesday, July 3 | @LA Angels | 9:05 PM | FS-M | KMOX 1120 |
| Thursday, July 4 | @LA Angels | 8:05 PM | FS-M | KMOX 1120 |
| Friday, July 5 | vs. Miami | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, July 6 | vs. Miami | 1:15 PM | FS-M | KMOX 1120 |
| Sunday, July 7 | vs. Miami | 1:15 PM | FS-M | KMOX 1120 |
| Tuesday, July 9 | vs. Houston | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, July 10 | vs. Houston | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, July 11 | @Chi Cubs | 7:05 PM | FS-M | KMOX 1120 |
| Friday, July 12 | @Chi Cubs | TBD | FS-M | KMOX 1120 |
| Saturday, July 13 | @Chi Cubs | 6:15 PM | FOX | KMOX 1120 |
| Sunday, July 14 | @Chi Cubs | 7:05 PM | ESPN | KMOX 1120 |
| Friday, July 19 | vs. San Diego | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, July 20 | vs. San Diego | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, July 21 | vs. San Diego | 1:15 PM | FS-M | KMOX 1120 |
| Tuesday, July 23 | vs. Philadelphia | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, July 24 | vs. Philadelphia | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, July 25 | vs. Philadelphia | 6:15 PM | FS-M | KMOX 1120 |
| Friday, July 26 | @Atlanta | 6:30 PM | FS-M | KMOX 1120 |
| Saturday, July 27 | @Atlanta | 2:05 PM | FOX | KMOX 1120 |
| Sunday, July 28 | @Atlanta | 12:35 PM | FS-M | KMOX 1120 |
| Monday, July 29 | @Pittsburgh | 6:05 PM | FS-M | KMOX 1120 |
| Tuesday, July 30 | @Pittsburgh | 3:05 PM | FS-M | KMOX 1120 |
| Tuesday, July 30 | @Pittsburgh | Game 2 | FS-M | KMOX 1120 |
| Wednesday, July 31 | @Pittsburgh | 6:05 PM | FS-M | KMOX 1120 |
| Thursday, August 1 | @Pittsburgh | 6:05 PM | FS-M | KMOX 1120 |
| Friday, August 2 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Saturday, August 3 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Sunday, August 4 | @Cincinnati | 12:10 PM | FS-M | KMOX 1120 |
| Monday, August 5 | vs. LA Dodgers | 6:05 PM | FS-M | KMOX 1120 |
| Tuesday, August 6 | vs. LA Dodgers | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, August 7 | vs. LA Dodgers | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, August 8 | vs. LA Dodgers | 7:15 PM | FS-M | KMOX 1120 |
| Friday, August 9 | vs. Chi Cubs | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, August 10 | vs. Chi Cubs | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, August 11 | vs. Chi Cubs | 1:15 PM | KMOX 1120 | |
| Tuesday, August 13 | vs. Pittsburgh | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, August 14 | vs. Pittsburgh | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, August 15 | vs. Pittsburgh | 12:45 PM | FS-M | KMOX 1120 |
| Friday, August 16 | @Chi Cubs | TBD | FS-M | KMOX 1120 |
| Saturday, August 17 | @Chi Cubs | 12:05 PM | FS-M | KMOX 1120 |
| Sunday, August 18 | @Chi Cubs | TBD | FS-M | KMOX 1120 |
| Monday, August 19 | @Milwaukee | 7:10 PM | FS-M | KMOX 1120 |
| Tuesday, August 20 | @Milwaukee | 7:10 PM | FS-M | KMOX 1120 |
| Wednesday, August 21 | @Milwaukee | 1:10 PM | FS-M | KMOX 1120 |
| Thursday, August 22 | vs. Atlanta | 7:15 PM | FS-M | KMOX 1120 |
| Friday, August 23 | vs. Atlanta | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, August 24 | vs. Atlanta | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, August 25 | vs. Atlanta | 1:15 PM | FS-M | KMOX 1120 |
| Monday, August 26 | vs. Cincinnati | 6:05 PM | FS-M | KMOX 1120 |
| Tuesday, August 27 | vs. Cincinnati | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, August 28 | vs. Cincinnati | 7:15 PM | FS-M | KMOX 1120 |
| Friday, August 30 | @Pittsburgh | 6:05 PM | FS-M | KMOX 1120 |
| Saturday, August 31 | @Pittsburgh | 6:05 PM | FS-M | KMOX 1120 |
| Sunday, September 1 | @Pittsburgh | 12:35 PM | FS-M | KMOX 1120 |
| Monday, September 2 | @Cincinnati | 12:10 PM | FS-M | KMOX 1120 |
| Tuesday, September 3 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Wednesday, September 4 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Thursday, September 5 | @Cincinnati | 6:10 PM | FS-M | KMOX 1120 |
| Friday, September 6 | vs. Pittsburgh | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, September 7 | vs. Pittsburgh | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, September 8 | vs. Pittsburgh | 1:15 PM | FS-M | KMOX 1120 |
| Tuesday, September 10 | vs. Milwaukee | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, September 11 | vs. Milwaukee | 7:15 PM | FS-M | KMOX 1120 |
| Thursday, September 12 | vs. Milwaukee | 7:15 PM | FS-M | KMOX 1120 |
| Friday, September 13 | vs. Seattle | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, September 14 | vs. Seattle | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, September 15 | vs. Seattle | 1:15 PM | FS-M | KMOX 1120 |
| Monday, September 16 | @Colorado | 7:40 PM | FS-M | KMOX 1120 |
| Tuesday, September 17 | @Colorado | 7:40 PM | FS-M | KMOX 1120 |
| Wednesday, September 18 | @Colorado | 7:40 PM | FS-M | KMOX 1120 |
| Thursday, September 19 | @Colorado | 2:10 PM | FS-M | KMOX 1120 |
| Friday, September 20 | @Milwaukee | 7:10 PM | FS-M | KMOX 1120 |
| Saturday, September 21 | @Milwaukee | 6:10 PM | FS-M | KMOX 1120 |
| Sunday, September 22 | @Milwaukee | 1:10 PM | KMOX 1120 | |
| Monday, September 23 | vs. Washington | 7:15 PM | FS-M | KMOX 1120 |
| Tuesday, September 24 | vs. Washington | 7:15 PM | FS-M | KMOX 1120 |
| Wednesday, September 25 | vs. Washington | 12:45 PM | FS-M | KMOX 1120 |
| Friday, September 27 | vs. Chi Cubs | 7:15 PM | FS-M | KMOX 1120 |
| Saturday, September 28 | vs. Chi Cubs | 6:15 PM | FS-M | KMOX 1120 |
| Sunday, September 29 | vs. Chi Cubs | 1:15 PM | FS-M | KMOX 1120 |
