| # | Pitchers | B/T | Ht | Wt | DOB |
|---|---|---|---|---|---|
| 32 | Craig Breslow | L-L | 6'1" | 190 | Aug 8, 1980 |
| 11 | Clay Buchholz | L-R | 6'3" | 190 | Aug 14, 1984 |
| 65 | Jose De La Torre | R-R | 5'10" | 185 | Oct 17, 1985 |
| 46 | Ryan Dempster | R-R | 6'2" | 215 | May 3, 1977 |
| 22 | Felix Doubront | L-L | 6'2" | 225 | Oct 23, 1987 |
| 41 | John Lackey | R-R | 6'6" | 235 | Oct 23, 1978 |
| 31 | Jon Lester | L-L | 6'4" | 240 | Jan 7, 1984 |
| 30 | Andrew Miller | L-L | 6'7" | 210 | May 21, 1985 |
| 59 | Clayton Mortensen | R-R | 6'4" | 185 | Apr 10, 1985 |
| 36 | Junichi Tazawa | R-R | 5'11" | 200 | Jun 6, 1986 |
| 19 | Koji Uehara | R-R | 6'2" | 195 | Apr 3, 1975 |
| 63 | Alex Wilson | R-R | 6'0" | 215 | Nov 3, 1986 |
| # | Catchers | B/T | Ht | Wt | DOB |
| 20 | Ryan Lavarnway | R-R | 6'4" | 240 | Aug 7, 1987 |
| 39 | Jarrod Saltalamacchia | S-R | 6'4" | 235 | May 2, 1985 |
| # | Infielders | B/T | Ht | Wt | DOB |
| 37 | Mike Carp | L-R | 6'2" | 210 | Jun 30, 1986 |
| 23 | Pedro Ciriaco | R-R | 6'0" | 180 | Sep 27, 1985 |
| 7 | Stephen Drew | L-R | 6'0" | 190 | Mar 16, 1983 |
| 16 | Will Middlebrooks | R-R | 6'3" | 220 | Sep 9, 1988 |
| 12 | Mike Napoli | R-R | 6'0" | 220 | Oct 31, 1981 |
| 15 | Dustin Pedroia | R-R | 5'8" | 165 | Aug 17, 1983 |
| # | Outfielders | B/T | Ht | Wt | DOB |
| 2 | Jacoby Ellsbury | L-L | 6'1" | 195 | Sep 11, 1983 |
| 5 | Jonny Gomes | R-R | 6'1" | 230 | Nov 22, 1980 |
| 29 | Daniel Nava | S-L | 5'11" | 200 | Feb 22, 1983 |
| 18 | Shane Victorino | S-R | 5'9" | 190 | Nov 30, 1980 |
| # | Designated Hitter | B/T | Ht | Wt | DOB |
| 34 | David Ortiz | L-L | 6'4" | 250 | Nov 18, 1975 |
